Jump to ContentJump to Main Navigation
Amphibian DeclinesThe Conservation Status of United States Species$
Users without a subscription are not able to see the full content.

Michael Lannoo

Print publication date: 2005

Print ISBN-13: 9780520235922

Published to California Scholarship Online: March 2012

DOI: 10.1525/california/9780520235922.001.0001

Show Summary Details
Page of

PRINTED FROM CALIFORNIA SCHOLARSHIP ONLINE (www.california.universitypressscholarship.com). (c) Copyright University of California Press, 2020. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in CALSO for personal use.date: 27 May 2020

Lucké Renal Adenocarcinoma

Lucké Renal Adenocarcinoma

Chapter:
(p.96) Seventeen Lucké Renal Adenocarcinoma
Source:
Amphibian Declines
Author(s):

Robert G. Mckinnell

Debra L. Carlson

Publisher:
University of California Press
DOI:10.1525/california/9780520235922.003.0017

The Lucké renal adenocarcinoma of northern leopard frogs (Rana pipiens) was originally described by Balduin Lucké during the 1930s. The depletion of frog populations has been a major concern of herpetologists worldwide. One study has investigated the cell biology of the Lucké renal adenocarcinoma since 1958. Early in these studies, it became obvious that the best way to obtain frog renal adenocarcinomas for experimental studies was to study frogs in natural populations. In retrospect, it seems curious that an investigation into the cell biology of a frog neoplasm would lead to early recognition of frog population declines. The history of the Lucké renal adenocarcinoma of northern leopard frogs is impressive in that these studies led to the notions that herpesviruses can cause cancer, that there was a problem with frog populations in the upper Midwest, and that differentiation therapy may lead to a new form of cancer treatment. This chapter reviews past and present investigations of the Lucké renal adenocarcinoma that afflicts northern leopard frogs. It examines the pathology, epidemiology, and etiology of the Lucké renal adenocarcinoma.

Keywords:   Lucké renal adenocarcinoma, northern leopard frogs, Rana pipiens, Balduin Lucké, cell biology, population declines, differentiation therapy, pathology, epidemiology, etiology

California Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.

Please, subscribe or login to access full text content.

If you think you should have access to this title, please contact your librarian.

To troubleshoot, please check our FAQs, and if you can't find the answer there, please contact us.