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Experimental EvolutionConcepts, Methods, and Applications of Selection Experiments$
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Print publication date: 2009

Print ISBN-13: 9780520247666

Published to California Scholarship Online: March 2012

DOI: 10.1525/california/9780520247666.001.0001

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PRINTED FROM CALIFORNIA SCHOLARSHIP ONLINE (www.california.universitypressscholarship.com). (c) Copyright University of California Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in CALSO for personal use.date: 22 September 2021

Understanding Evolution through the Phages

Understanding Evolution through the Phages

(p.390) (p.391) 14 Understanding Evolution through the Phages
Experimental Evolution

Samantha E. Forde

Christine M. Jessup

University of California Press

This chapter focuses on empirical tests of evolutionary theory using viruses, specifically bacteriophage or phage, beginning by reviewing phage biology and the phage life cycle, and then describing laboratory procedures for cultivating phage and assaying fitness. It also reviews the theoretical models that have been used to describe phage ecology and evolution, in order to emphasize the advantages of using phage experimental systems to test theoretical predictions. The chapter then discusses recent phage experiments that have investigated the genetic basis and molecular mechanisms underlying adaptation. Finally, it emphasizes that the insights gained from experimental evolution studies with phage have important implications not only for phage ecology and evolution, but also for predator–prey and host–parasite interactions in general.

Keywords:   evolutionary theory, viruses, bacteriophage, phage, adaptation, experimental evolution

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