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Sequence AlignmentMethods, Models, Concepts, and Strategies$
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Michael Rosenberg

Print publication date: 2009

Print ISBN-13: 9780520256972

Published to California Scholarship Online: March 2012

DOI: 10.1525/california/9780520256972.001.0001

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Strategies for Efficient Exploitation of the Informational Content of Protein Multiple Alignments

Strategies for Efficient Exploitation of the Informational Content of Protein Multiple Alignments

Chapter:
(p.271) Chapter 11 Strategies for Efficient Exploitation of the Informational Content of Protein Multiple Alignments
Source:
Sequence Alignment
Author(s):

Anne Friedrich

Olivier Poch

Luc Moulinier

Publisher:
University of California Press
DOI:10.1525/california/9780520256972.003.0011

This chapter focuses on the multiple sequence alignment (MSA) of complete proteins. It first provides an overview of the central role of multiple sequence alignments and their use in a wide range of biological applications, particularly in protein analysis, and then discusses the problem of efficient MSA construction, depending on the biological question being studied. Finally, the chapter considers how the standard applications can be integrated for wider exploitation.

Keywords:   multiple sequence alignment, MSA, proteins, protein analysis, MSA construction

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