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Sequence AlignmentMethods, Models, Concepts, and Strategies$
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Michael Rosenberg

Print publication date: 2009

Print ISBN-13: 9780520256972

Published to California Scholarship Online: March 2012

DOI: 10.1525/california/9780520256972.001.0001

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PRINTED FROM CALIFORNIA SCHOLARSHIP ONLINE (www.california.universitypressscholarship.com). (c) Copyright University of California Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in CALSO for personal use.date: 30 July 2021

Computing Multiple Sequence Alignment with Template-Based Methods

Computing Multiple Sequence Alignment with Template-Based Methods

(p.54) (p.55) Chapter 4 Computing Multiple Sequence Alignment with Template-Based Methods
Sequence Alignment

Cédric Notredame

University of California Press

This chapter examines the major approaches for multiple sequence alignment (MSA), including matrix- and consistency-based approaches, and focuses on the latest developments, including the development of meta-methods and the emergence of template-based alignment techniques. It also considers the effect of reference benchmarks on the recent development of MSA packages, and their potential shortcomings.

Keywords:   multiple sequence alignment, MSA, matrix-based approaches, consistency-based approaches, meta-methods, template-based alignment

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