This chapter presents a synthesis of the key themes discussed in the preceding chapters. It argues that addiction is biocultural: the social imaginary determines biological outcomes, because what addicted people think of themselves and see as possible drives their risk of overdose, infection, violence, and incarceration. The question is how to cultivate social imaginaries and lattices of relationships that foster therapeutic ways of living. Pentecostalism can, at times, open spaces for marginal people to create a new order based on narratives of ascetic redemption, domesticity, and universal access to knowledge and gifts. At other times, it draws on elements of the old order—such as patriarchy—empowering some members at the expense of others.